Abstract

Segmentation of stem cells is a challenging process in image processing where level set method is used extensively. This level set criterion with re-initialisation process reduces its wider range of application. Thus re-initialisation is eradicated by a method called distance regularisation in which the signed distance property is maintained near the zero level set via forward and backward (FAB) diffusion effect. A potential function is habituated to sustain the desired shape of the level set function. The initial potential function used in distance regularisation is single-well potential technique that causes excess backward diffusion and oscillation in LSF, so it is succeeded by double-well potential. But this double well technique losses the capability to conserve the regularity at some points. This problem is eliminated by a new novel method called improved diffusion rate with triple-well potential. The proposed diffusion rate can maintain the signed distance property of the level set function (LSF) and overcome the side effect of double-well potential with reduced number of iterations.

Highlights

  • Stem cells are unique cells of the body in that they are unspecialized and have the ability to develop in to several different types of cells

  • The main aim of this paper is to obtain the improved segmentation method to acquire the preliminary process in order to examine the growth rate of stem cells in future

  • Segmentation is one of the emphasise method in an image processing. It deals with sectionalisation of an image into multiple parts to recognize the objects like colour, texture, grey value, etc. and image segmentation is the process of assigning a label to every pixel in an image such that pixels with the same label share certain characteristics

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Summary

Introduction

Stem cells are unique cells of the body in that they are unspecialized and have the ability to develop in to several different types of cells. Before injecting stem cells to the patients, first we have to analyse whether it is healthy or not They are different from specialized cells, such as heart or blood cells and can replicate themselves. The main aim of this paper is to obtain the improved segmentation method to acquire the preliminary process in order to examine the growth rate of stem cells in future. Segmentation is one of the emphasise method in an image processing It deals with sectionalisation of an image into multiple parts to recognize the objects like colour, texture, grey value, etc. There are many types of segmentation like thresholding, colour-based segmentation, transform method, texture based segmentation, partial differential equation-based method, etc. The level set method (LSM) is based on partial differential equations (PDE), i.e. active evaluation of the differences among neighbouring pixels to find object boundaries. The LSM method is mainly used for the image segmentation and it find its application in image science

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