Abstract

Psoriasis is an inflammatory skin disease that has been linked to both genetic and environmental factors. From 0.09 to 11.43% of the world's population has this dermatosis; in industrialized nations, the prevalence is between 1.5% and 5%. Psoriasis is believed to be caused by a combination of adaptive and innate immune responses. The PASI scale measures the clinical severity of psoriasis on a scale from 0 to 100. This analysis was conducted to determine if existing nutrition interventions are effective in alleviating psoriasis symptoms. Science Direct, Google Scholar, Scopus, PubMed, and ClinicalTrials.gov were used to compile the data for this review. We used the following search terms to narrow our results: psoriasis, nutrition, diet treatment, vitamin, RCTs, and clinical trials. Ten studies were selected from the 63 articles for this review. Research designs are evaluated using the Risk of Bias 2 (RoB2), the Risk of Bias in Non-Randomized Studies of Interventions (ROBINS-I), and the Newcastle-Ottawa Scale (NOS). Studies concluded that a Mediterranean diet, vitamin D3 supplementation, the elimination of cadmium (Cd), lead (Pb), and mercury from the diet, as well as intermittent fasting and low-energy diets for weight loss in obese patients, can alleviate the symptoms of inflammatory diseases. Psoriasis patients undergoing treatment should adhere to dietary recommendations.

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