Abstract

FOLLOWING the work of Deanesly and Parkes in 1937 (1) on the subcutaneous W implantation of crystals of androgens and estrogens one of us (S.A.V.) began JL a study to determine the effects of testosterone and its various esters in the human male after subcutaneous injection and in the form of implanted pellets (2–6). The work of Deanesly and Parkes was in rodents and fowls and with possible widespread clinical implications it seemed important to investigate the effects of pellet implantation in the monkey and attempt to compare the effect of implantation of crystalline testosterone with that following injections of testosterone propionate in oil. Observations on the effect of subcutaneous injections of testosterone propionate n i the monkey have been reported (7–10). It has been well established that testc sterone propionate in the form of subcutaneous injections will restore the atrophied accessory reproductive organs of the castrate mature or immature male rhesus monkey to normal adult size and function...

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