Implant-Associated Giant Cell Granuloma: A Case Report of 4.8-Year Follow-up and Literature Review.

Abstract

Objective. The aim of this case report was to document a case of implant associated central giant cell granuloma (CGCG) and review the literature on implant associated and intrabony lesions. CGCG is most common in females and usually seen in the mandible from anterior to posterior. Based on its clinical, radiological, and histological findings, it can be classified as aggressive and non-aggressive forms. Trauma is considered a major etiological factor for the lesion. Even peripheral giant cell granuloma has been shown as a peri-implant lesion, CGCG has not been reported as an implant-associated pathology. In this case report, we reported that CGCG developed after implant placement in 8 months. 39-year-old female patient with partial edentulism in the posterior mandible presented to our clinic. She had reported that she lost her posterior mandible teeth for more than six years. Initial clinical and radiological examination revealed that she showed localized slight to moderate chronic periodontitis, horizontal ridge deficiency (in the posterior mandible), and cavities. A total of six implants were placed at the same time. At 8-month of the surgery, she showed a radiolucency area #34 area. The lesion was enucleated, and the defect area was filled up with a xenogeneic bone substitute. The healing was uneventful. The histological examination determined the lesion was CGCG. The lesion showed no recurrency for 4.8 years.