Abstract
Ziele: To determine accuracy and feasibility of a magnetic resonance (MR) imaging approach for depicting impaired diastolic function in hypertensive patients. Methode: 27 Patients (19 men and 8 women; mean age 57±13 years) were assessed by echocardiography and MRI in order to compare ejection fraction (EF) and E/A ratio measured by each method. By using of echocardiography all patients were graded according to the findings into normal, pseudo-normal and patients showing impaired relaxation of the left ventricle or severe diastolic dysfunction. The MR imaging protocol included cine short axis sequences for the assessment of the EF and a velocity encoded flow measurement over the mitral valve. Statistical analysis was made by using Bland-Altman's correlation and Lin's concordance correlation. Ergebnis: MRI and Doppler measurements could be correlated in all 27 patients. In MRI 8 patients were graded as normal, 11 patients as pseudonormal, 3 patients as having impaired left ventricular relaxation and 5 patients as having severe diastolic dysfunction. Agreement between MRI and Doppler regarding EF was statistically not significant (1. Bland-Altman correlation: r=0.33, p=0.13; 2. Lin-concordance: r=0.31, p=0.12) whereas E/A ratio measurements was statistically significant in correlation (r=0.46, p=0.03) and showed significant concordance(r=0.29, p=0.03, 95%-CI for r:[0.03; 0.52]). Schlussfolgerung: MR imaging is an accurate means of assessing diastolic function in patients with known history of hypertension.
Published Version
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a call