Abstract

The emergence of the Omicron variant has posed significant challenges to the effectiveness of existing vaccines and antibody-based therapies in combating COVID-19. This systematic literature review examines the impact of wellness on vaccine hesitancy related to the Omicron variant. The review explores various factors influencing vaccine hesitancy, including demographic characteristics, health literacy, historical mistrust, and misinformation. The research investigates the role of clear and consistent messaging, trust-building measures, and collaboration among stakeholders in addressing vaccine hesitancy. The findings indicate that a considerable percentage of the population expresses vaccine hesitancy, particularly among younger individuals and females. The review concludes by discussing the implications of parental attitudes towards vaccinating children, the impact of confidence and collective responsibility, and the influence of various antecedents on vaccine hesitancy. The findings provide valuable insights for policymakers, healthcare professionals, and public health authorities to design effective strategies to address vaccine hesitancy and enhance vaccination rates, thus mitigating the impact of the Omicron variant and future variants.

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