Abstract
Objective This study explores the effect of sarcopenia on quality of life and mobility in elderly (COPD) patients. Methods Elderly COPD patients from Ruijin Hospital (July 2019–April 2021) were divided into sarcopenia and non-sarcopenia groups. Data were analyzed to assess the correlation between muscle indices and COPD parameters. Results There were 32 patients in sarcopenia group and 60 patients in non-sarcopenia group. Patients in the sarcopenia group were significantly older than those in the non-sarcopenia group (p < 0.05). Additionally, hemoglobin, albumin, body mass index (BMI), grip strength, 6-meter walking speed, appendicular skeletal muscle mass (ASM), and skeletal muscle index (SMI) were significantly lower in the sarcopenia group (p < 0.01). SMI was identified as an independent risk factor for reduced quality of life and mobility in COPD patients (p < 0.05). Conclusion Sarcopenia is a common complication in elderly COPD patients and is strongly associated with decreased quality of life and mobility.
Published Version
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