Abstract
RBCT is still a subject of debate with 2 main questions: what is the optimal threshold? and does transfusion impact the outcome?. Concerning septic patients, a threshold of 10 g/dL was for many years the objective during the first hours of septic shock and since the last surviving sepsis campaign, a threshold of 7 g/dL for stabilized septic patients is proposed. Nevertheless, the evidence base dealing with septic patients remains poor and cohort studies bring divergent results.
Highlights
RBCT is still a subject of debate with 2 main questions: what is the optimal threshold? and does transfusion impact the outcome?
In the sub group analysis of the studies specific of septic patients (n=7), mortality was unaffected by RBCT
The heterogeneity could be explained by the statistical methods)
Summary
The aim of this study was to achieve a systematic review and meta-analysis on the impact of RBCT among septic ICU adults
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