Abstract
Objective To ascertain the impact of long referral to first colposcopy interval on disease outcome in women with high-grade cervical smear tests. Methods Data from 316 women categorized into Group 1 (seen 180 days after referral) and Group 2 (seen within 180 days of referral) were analyzed using χ 2 test with Yates correction. Odds ratios (OR) and 95% confidence intervals (CI) were calculated. Results Women in Group 1 were less likely to need treatment (33.8% [25/74] vs 55.8% [135/242]; OR = 0.45; 95% CI, 0.25–0.78; P = 0.0004) and less likely to have high-grade disease (24.3% [18/74] vs 45.9% [111/242]); OR = 0.37; 95% CI, 0.21–0.68; P = 0.001) than women in Group 2. There was no significant difference between the groups in proportion of women with invasive disease. Conclusion In women with high-grade smears the need for excisional treatment and the risk of invasive disease may be reduced by prolonged referral interval.
Published Version
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