Impact of preweaning vaccination on host response in healthy calves during the cow-calf phase of production

Abstract

One of the most important tools used in managing and prevent­ing bovine respiratory disease (BRD) is vaccination. Although numerous licensed products exist for various viral and bacteri­al BRD pathogens, the impact of vaccinating young calves prior to weaning on host gene expression is unknown. Therefore, our objective is to explore differences in host gene expression in calves that were vaccinated preweaning or not via time-course transcriptomics.