Abstract
Background Hyperglycemia is common and related to more morbidity and death rates in hospitalized patients with acute coronary syndromes (ACS). We planned to research the relationship between the glycemic state and the hospital outcomes in ACS patients. Methods It was a prospective cohort study in included 150 patients admitted to the coronary care unit (CCU) with ACS at Sohag University hospital and were followed up for one month. We classified the patients into three gatherings regarding their glycemic state, group A (euglycemic), group B (hyperglycemia and not diabetic), and group C (hyperglycemia and known to be diabetic). Results We found no significant difference in the individual hospital outcomes, including serious arrhythmia, acute pulmonary edema, cardiogenic shock, recurrent ischemia, heart failure, cerebrovascular stroke (CVS), or all-cause deaths in the three groups. There was a significantly higher total outcome in hyperglycemic patients (group B+ C) compared to euglycemic patients (group A) after multivariate regression analysis and confounders adjustment (Adjusted OR was 1.79; 95% CI 1.31-3.12; p-value 0.01). Conclusion:In both diabetic and non-diabetic patients presented with ACS, the admission hyperglycemia has a harmful impact on the hospital outcomes. So, strict monitoring of the blood glucose levels at admission for all ACS patients is required, and tight management of hyperglycemia is mandatory.
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