Abstract
Purpose: A previous meta-anlysis of studies involving healthy animals demonstrated that a moderate daily dose of exercise may be chondroprotective. However, it remains unknown if exercise following joint injury may either accelerate posttraumatic changes or have a chondroprotective effect in animal models of posttraumatic osteoarthritis (PTOA). The purpose of the current systematic review and meta-analysis was to evaluate the role of exercise on knee cartilage changes in animals with either anterior cruciate ligament or medial meniscus transection.
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