Abstract
Purpose INTERMACS data show that select AE’s lead to higher mortality during VAD support. However, the extent to which these AE’s experienced early (within 60 days) after VAD implant effect long-term survival after this time period is not known for those with a CF-VAD. Methods and Materials We analyzed prospectively collected data from a single-center database on adults implanted with a CF-VAD (2004-2011) who survived beyond 60 days. 14 different classes of AE’s as defined by INTERMACS were assessed during the first 60 days post-implant. For each AE, 1-year survival was compared for those with and without the AE using Kaplan-Meier analysis. Any class of AEs at least marginally associated (p Results In 91 patients, the mean age was 56 years, 81% were male, 82% were white, and 65% were bridge to transplant. The occurrence of right ventricular failure (RVF), renal, neurologic, and respiratory events in the first 60 days of support were associated with significantly increased mortality at 12 months (p figure 1 ] Conclusions Of the 14 major AE’s experienced early after CF-VAD implantation, only RVF, renal, neurologic, and respiratory events had significant long-term effects on mortality that persisted beyond the initial event. The only early AE that was an independent predictor of poor late outcome was RVF.
Published Version
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