Abstract
Chronic kidney disease (CKD) is associated with poorer short and long-term cardiovascular morbidity and mortality. Even after the commencement of haemodialysis in end stage renal failure patients, mortality exceeds 20% in the first year1. More than 50% of these deaths are contributed by cardiovascular diseases (CVD), of which 20% are caused by acute myocardial infarction2. Consequent to these findings, the degree and impact of coronary revascularization on CKD patients represents a clinical challenge, especially in the setting of advanced stages of CKD.
Highlights
Chronic kidney disease (CKD) is associated with poorer short and long-term cardiovascular morbidity and mortality
More than 50% of these deaths are contributed by cardiovascular diseases (CVD), of which 20% are caused by acute myocardial infarction[2]
This review aims to look at the latest evidence in the evolution of percutaneous coronary intervention (PCI), and whether this has led to improved CVD outcomes in CKD patients
Summary
Chronic kidney disease (CKD) is associated with poorer short and long-term cardiovascular morbidity and mortality. More than 50% of these deaths are contributed by cardiovascular diseases (CVD), of which 20% are caused by acute myocardial infarction[2]. Consequent to these findings, the degree and impact of coronary revascularization on CKD patients represents a clinical challenge, especially in the setting of advanced stages of CKD. 2. CKD patients tend to develop multivessel CAD with significant coronary calcifications, this in turn is strongly associated with exercise induced ischemia, as observed by stress echocardiographic studies[5]. Dialysis patients fare worse against the general population in terms of 1-year and 5-year CVD risk projections when matched for the same conventional CVRFs (such as age, gender, total cholesterol, systolic BP etc), as shown in the US National Health and Nutrition Examination[9]
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