Abstract
The use of the third generation cephalosporin, ceftiofur, is common in animal agriculture for the treatment of a wide range of production-limiting disease conditions. The therapeutic use of ceftiofur in livestock can select for the blaCMY-2 genetic element in the intestinal flora. The presence of resistant organisms is a potential public health threat to the consumer. This project investigated the impact of ceftiofur removal from cattle populations and the meat products they produced.
 The working hypothesis is that the use of ceftiofur in food animal populations selects for the emergence and rapid dissemination of third generation cephalosporin resistant microorganisms, leading to the potential risk of food-borne zoonotic pathogen transfer via the food chain.
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