Impact of case volume on performance of targeted temperature management, incidence of adverse events, and neurologic outcome in comatose out-of-hospital cardiac arrest survivors treated with targeted temperature management: A propensity score matching analysis

Abstract

s / Resuscitation 85S (2014) S15–S121 S97 off number between low volume and high volume hospital was 15.5 per year. The high volume hospitals started TTM significantly earlier following ROSC and had lower rate of hyperglycaemia, bleeding, hypotension, and rebound hyperthermia. However, good neurologic outcome and in-hospital mortality were comparable between high volume (27.7% and 44.6%, respectively) and low volume hospitals (21.1% and 40.5%) in the propensity matched cohort. The adjusted odds ratio in the high volume hospitals compared to lowvolumehospitalswere1.506 (95% confidence interval: 0.875–2.592) for poor neurologic outcome. Conclusions: The higher case volume of TTM was significantly associated with early initiation of TTM and lower incidence of adverse events. However, the case volume had no association with the neurologic outcome and in-hospital mortality. http://dx.doi.org/10.1016/j.resuscitation.2014.03.239