Abstract
e17537 Background: Effective management of ES/OS/RMS requires a multidisciplinary approach. Whether care at specialized centers (e.g., NCICCCs) affords a survival advantage across socioeconomic strata remains unstudied. Methods: We constructed a population-based cohort of 629 patients with newly diagnosed (dxed) ES/OS/RMS reported to Los Angeles cancer registry between 1998 and 2008. Multivariable Cox regression was used to determine impact of care at NCI sites (NCICCCs [all ages]; Children’s Oncology Group [COG] sites [<21y]) on overall survival adjusting for dx, stage, age, SES, payor. Logistic regression was used to determine likelihood of care at NCI sites, adjusting for above variables and distance to nearest center (using GIS). Results: Clinical characteristics in Table.Median age at dx was 17y (0-65y). Survival: Multivariable analysis revealed payor as a risk factor for survival (uninsured: HR=1.7, 95%CI 1.0-2.8, p=0.04; ref: private insurance). A significant NCI/payor interaction (p=0.01) was obse...
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