Abstract

A two-dimensional dual material double hetero stack gate (DMDG-HSG-MOSFET) based biosensor is proposed for the identification of label-free biomolecules like uricase (K = 1.54), streptavidin (K = 2.10), ferrocytochrome C(K = 4.7), and protein (K = 8). The influence of the biomolecule's position and filling area (100%, 66.66%, and 33.33%) has been inspected to detect the device sensitivity. The electrical parameters like device current, threshold voltage, current sensitivity, voltage sensitivity, and subthreshold performance of the device are examined by considering the neutral biomolecules. Further, the device performance optimization has been done by varying the oxide thickness (tox) using the dielectric modulation method. The performance parameters are analyzed for the biomolecules filling areas 100%, 66.66% and 33.33% and the analysis provides better results with protein biomolecule. For protein biomolecule with a 100% filling area the threshold voltage, current, and subthreshold swing sensitivities are obtained as 0.69, 1.96, and 1.09 respectively.

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