Impact of anemia on HbAC level in type 2 diabetes mellitus patients

Abstract

HbA1c is one of the important laboratory markers of blood glucose levels monitoring over last 2-3 months. Studies have shown that many factors affect HbA1c levels, hence it is not the only investigation to diagnose diabetes mellitus. As both iron deficiency anaemia and diabetes mellitus are highly prevalent disorders, effect of iron deficiency anaemia on HbA1C need to be evaluated. Many factors such as haemolytic anaemia, vitamin deficiencies, pregnancy. Kidney disease, haemoglobin variants can affect HbA1C levels. This study had two groups of participants. Group 1 included diabetic patients with iron deficiency anaemia and group 2 included diabetic patients without iron deficiency anaemia. Significant correlation between HbA1C and iron deficiency anaemia has been found. PCV, MCH, MCHC, MCV are low in diabetics with Iron deficiency anaemia and high in diabetics without iron deficiency anaemia. Need for anaemia screening before treatment planning of diabetes based on HBA1C levels must be considered and for optimal diabetes control, treating anemia is necessary.