Abstract
Immunotherapy and gastroenteropancreatic neuroendocrine tumor
Highlights
Gastroenteropancreatic Neuroendocrine Tumor (GEP-neuroendocrine tumors (NETs)) originates from the hormone producing cells of the gut along with rectum and pancreas
According to a study conducted by Kawahara et al, the locus p21, present on chromosome 6p12 was over expressed in 66% cases of GI NETs of malignant origin
Gastroenteropancreatic Neuroendocrine Tumor (GEP-NET) belong to the class of NETs
Summary
Gastroenteropancreatic Neuroendocrine Tumor (GEP-NET) originates from the hormone producing cells of the gut along with rectum and pancreas. GEP-NET represents 75% of all neuroendocrine tumors (NETs) [2]. There is an increase of about 400% in the incidence since the past 3 decades [4,5]. It includes different types of histopathological and genetic characteristics. GEP-NETs develop in hormone producing cells in the gut and pancreatic areas. They are classified on the basis of embryonic site of origin and the hormones secreted by them, in the course. The classifications of GEP-NETs are as follows: 1. Functional Carcinoids: Aberrant/excessive secretion of serotonin
Sign-in/Register to view highlights & summary Sign-in/Register to access full text options 
Free) 
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a call
