Abstract
In this work, a bovine serum albumin (BSA) immunosensor based on graphene oxide (GO) modified cladding-etched excessively tilted fiber grating (ExTFG) is proposed, and the basic principle and sensing characteristics of the sensor are analyzed. Refractive index (RI) sensitivity of ExTFG is increased by 77.17% by etching its cladding diameter to 80μm. The cladding-etched ExTFG is coated with GO, and then BSA anti-monoclonal antibody (anti-MABs) are immobilized on its surface, so as to realize the special detection for BSA. Experimental results show that the sensitivity is about five times of that of the un-etched GO-coated ExTFG, the limit of detection (LOD) is ~0.165 nM by using optical spectrum analyzer with a resolution of 0.03nm.
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a callDisclaimer: All third-party content on this website/platform is and will remain the property of their respective owners and is provided on "as is" basis without any warranties, express or implied. Use of third-party content does not indicate any affiliation, sponsorship with or endorsement by them. Any references to third-party content is to identify the corresponding services and shall be considered fair use under The CopyrightLaw.
