Abstract
This study was carried out to determine immunomodulatory trace element zinc in HIV positive individuals. Serum zinc, albumin and total protein in twenty five HIV positive individuals were compared with twenty four HIV negative individuals (control).Methods: Atomic absorption spectrophotometer (AAS) method was adopted to determine concentration of zinc. Bromocresol green method and Biuret method were used respectively to determine albumin and total Protein respectively.Result:The mean ± SD for zinc is 0.2±0.13mg/l, Albumin 33.18±12.61g/l and total Protein 31.35±9.05g/l in HIV positive individuals while in the control the values are zinc 1.36±1.11mg/l, Albumin 39.68±13.20g/l and total protein 61.22±26.85g/l respectively. All three parameters were significantly low in HIV positive individuals than in HIV negative individuals. Zinc (P<0.05), Albumin (P<0.05) and total Protein (P<0.05). These changes were attributed to nutritional factors and destruction of cells in intestine by the immune system. Keynote: Zinc, immunomodulatory, trace elements, immune modulator, HIV and carrier proteins
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