Abstract
The purpose of the study was to study the immune status of patients diagnosed with SBK, to develop immunological diagnostic and prognostic criteria. It was found that SD3+- and SD4+-lymphocytes decreased by 1.43 and 1.07 times, SD8+-lymphocytes increased by 1.25 times, and IRI decreased by 1.32 times (T-immunodeficiency). SD25+ lymphocytes increased by 1.80 and 1.59 times, and SD95+ lymphocytes increased by 1.28 and 1.13 times in the blood of these patients. It was found that the amount of SD16+-lymphocytes was reliably increased compared to the parameters of healthy individuals. An imbalance was observed in the concentration of immunoglobulins in blood serum, while IL-4 increased by 11.84 times in patients, IL-6 was reliably reduced by 1.46 times compared to healthy people. Dynamic determination of serum concentrations of IL-4 and IL-6 was recommended as diagnostic and prognostic criteria for patients diagnosed with SBK.
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