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Abstract
Odontogenic cysts and tumours are lesions that are derived from the tooth producing tissues or their remnants that remain entrapped either within the jaw bones or into the adjacent soft tissues. From a biological point of view, some of these lesions represent hamartomas with varying degrees of differentiation, while the rest are benign or malignant neoplasm with variable aggressiveness and potential to develop metastasis. Immunohistochemistry is the in situ detection of specific antigens in tissue sections by means of an immunologic reaction (based on antigen -antibody binding). Today, immunohistochemistry has applications in a wide variety of oral lesions including cysts and tumours of odontogenic origin. The aim of this review will be to focus on the various aspects of immunohistochemistry in odontogenic cysts and tumours including its advantages, disadvantages, and applications & recent advances. keywords: immunohistochemistry, odontogenic cysts, odontogenic tumours, advantages, disadvantages.
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