Abstract
An immunohistochemical study of 128 female breast cancer patients in Varna is performed. The expression of estrogen and progesterone receptors, human epidermal growth factor receptor 2 (HER2) and proliferation marker protein Ki-67 in terms of histological and molecular types and differentiation grade is assessed. Ductal carcinoma and luminal B HER2(+) prevail. The discrepancies between immunohistochemical positivity and negativity of single biomarkers are outlined.
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