Abstract
Taurine is one of the most abundant free amino acids in animal tissues. It is not incorporated into proteins but found mainly in the free form. Taurine has long been regarded as a mere end product of sulphur amino acid metabolism with no physiological role except that of bile acid conjugation. Yet, recent studies have implicated taurine in many physiological events, including osmoregulation, anti-oxidation, detoxification, membrane stabilization and neuromodulation1–4. However, its localization and function in the stomach has not been previously analysed in detail. The aim of this study is to reveal the distribution of taurine in the rat stomach, and to define taurine-containing cells in this organ by immunohistochemical techniques.
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