Abstract
Objective: To study the histo-morphological spectrum of uterine smooth cell tumors withimmunohistochemical expression of estrogen and progesterone receptor and to compare theirexpression with respect to that of surrounding myometrium. Materials & Methods: The study is conducted at a tertiary care hospital in northern India which included themyomectomy as well as hysterectomy specimens of the smooth muscle cell tumor. This study found th Results: at the majority of leiomyoma tumors express positivity for estrogen and progesterone receptors, with one-third showing moderate expression and the rest showing strong expression. The study concludes that the majority of Conclusion: uterine smooth muscle tumors are benign and hormone receptor expression, particularly ER, may play a crucial role in their development and progression, highlighting the need for further research to improve diagnostic and treatment approaches. Additionally, a decrease in hormone receptor expression was observed as tumors progressed from benign to malignant, but the conclusion is limited due to the small number of tumors demonstrating atypical characteristics
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have