Abstract
One hundred ninety-two patients (82 males and 110 females) with three types of allergic diseases (allergic asthma 60, allergic rhinitis 54, and urticaria 78), and 45 control subjects were tested to determine the levels of IgG, IgM and IgA by using the single radial immunodiffusion technique, and the levels of IgE by the ELISA method. The results revealed an apparent increase in IgE levels and inversely significant decrement for both IgG and IgA in all the three types of the allergies. While there were no substantial differences between IgM levels in allergic asthma, urticaria, and control; only allergic rhinitis showed a significant decrease in the IgM level. The aim of this research is to investigate the relationship between serum level of IgG, IgM, IgA, and IgE in patients with allergic rhinitis, allergic asthma and urticaria. The decreasing level of IgG and IgA, as well as, increasing level of IgE, are associated with the three types of allergies and play an important role in developing the disease.
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