Abstract

Immunoglobulin levels (lgA, IgG and IgM) were examined in 41 cases of malignant lymphoma, consisting of 14 cases of Hodgkin's disease, 23 cases of reticulum cell sarcoma, and 4 cases of lymphosarcoma. Data were summarized as follows. I) Levels of the 3 classes of immunoglobulins tend to divert from the normal with aggravation of the clinical course. An improvement of the clinical course, on the other hand, tends to bring the immunoglobulin values to the normal range. 2) Low level of IgA in Hodgkin's disease and sarcoma group may be closely related to improvement in the lymphatic tissues, rather than due to treatment. 3) Statistically correlated IgA or IgG levels to pheripherallymphocyte counts lower than 1,500/cmm were also observed.

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