Abstract
To the Editor.— Crytpococcosis involves the lungs and the central nervous system. The causative organism,Cryptococcus neoformans, is frequently an opportunistic, secondary invader, associated with severe debilitating illness and drug treatments. The diagnosis depends on culture procedures and biochemical techniques performed on the positive cultures, as well as serological tests, tube agglutination, complement-fixation, immunodiffusion, and latex cryptococcal antigen agglutination tests.1-3 A patient with long-standing rheumatoid arthritis had received prednisone and chlorambucil and developed steroid-induced diabetes mellitus and subsequentCryptococcusmeningitis, which caused her death. A new rapid method utilizing indirect immunofluorescence to identify cryptococcal antigen and antibody in body fluids is described here. Report of a Case.— A 61-year-old white woman with a long history of rheumatoid arthritis since age 14 had been treated with prednisone and for a short period with chlorambucil. Adult onset diabetes mellitus developed that was probably steroid induced. Chlorambucil therapy was begun in early
Sign-in/Register to access full text options 
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a callMore From: JAMA: The Journal of the American Medical Association
Disclaimer: All third-party content on this website/platform is and will remain the property of their respective owners and is provided on "as is" basis without any warranties, express or implied. Use of third-party content does not indicate any affiliation, sponsorship with or endorsement by them. Any references to third-party content is to identify the corresponding services and shall be considered fair use under The CopyrightLaw.
