Abstract
Immune-Related Disorders and Extrahepatic Diseases in Chronic HCV Infection
Highlights
Within the infected host, Hepatitis C virus (HCV) exists as a quasispecies or a flock of related viral sequences
HCV is mainly characterized by two major immunologic fingerprints, namely, escape of immune response in more than 80% of infected patients and production of autoantibodies in almost half of them
While HCV evolves under immunological pressure, the cellular immune response remains focused on viral sequences encountered early in the course of the infection
Summary
HCV exists as a quasispecies or a flock of related viral sequences. Editorial Immune-Related Disorders and Extrahepatic Diseases in Chronic HCV Infection Hepatitis C virus (HCV) represents one of the most important causes of chronic active liver disease worldwide, potentially resulting in cirrhosis, and hepatocellular carcinoma.
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