Abstract
The discovery of the Raman effect in 1928 not only aided fundamental understanding about the quantum nature of light and matter but also opened up a completely novel area of optics and spectroscopic research that is accelerating at a greater rate during the last decade than at any time since its inception. This introductory overview focuses on some of the most recent developments within this exciting field and how this has enabled and enhanced disease diagnosis and biomedical applications. We highlight a small number of stimulating high-impact studies in imaging, endoscopy, stem cell research, and other recent developments such as spatially offset Raman scattering amongst others. We hope this stimulates further interest in this already exciting field, by 'illuminating' some of the current research being undertaken by the latest in a very long line of dedicated experimentalists interested in the properties and potential beneficial applications of light.
Highlights
The properties of light have been of interest to experimentalists for millennia
His research involving the rapid and quantitative detection of foodborne bacteria using FT-IR and machine learning has been widely publicised, featuring on BBC TV and radio, the Science Museum in London, as well as the national and international press (e.g. WIRED). He works at the Manchester Institute of Biotechnology (MIB), as a Senior Experimental Officer undertaking research and managing the labs of Roy Goodacre and Doug Kell, in the School of Chemistry, University of Manchester, UK
This study demonstrated the potential of Raman spectroscopy for noninvasive phenotypic identi cation of stem cells, though the authors themselves stated that it was not yet practical for medical applications due to their long spectral acquisition times
Summary
The properties of light have been of interest to experimentalists for millennia. From the publication of Ibn al-Haytham's seven aSchool of Chemistry, Manchester Institute of Biotechnology, The University of Manchester, 131 Princess Street, Manchester M1 7ND, UK.
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