Abstract
Macrophages activated via the IL-4 receptor possess non-immune functions that support tissue homeostasis, but their specific role in aging is unknown. In this issue of Immunity, Zhou etal. show that IL-4 extends lifespan by inducing DNA repair pathways that protect macrophages from cellular senescence.
Published Version
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have