Abstract
Irritable bowel syndrome (IBS) is a chronic disease with recurrent abdominal pain, disturbed bowel emptying, and changes in stool consistency. We compared the effectiveness of three different dietary treatment plans (G1-FM-low FODMAP diet, G2-IP IgG based elimination-rotation-diet, and as control group, the G3-K control diet recommended by an attending gastroenterologist) in treating patients diagnosed with mixed irritable bowel syndrome. A total of seventy-three female patients diagnosed with a mixed form of irritable bowel syndrome (IBS-M) were enrolled in the study. The diet of each patient in Group 1 (G1-FM) and 2 (G2-IP) was determined individually during a meeting with a dietitian. Patients from Group 3 (G3-K) received nutrition advice from a gastroenterologist. Significant differences in the reduction of IBS symptoms were found between the groups. IBS symptoms as well as comorbid symptoms significantly improved or disappeared completely in the G2-IP group (idiopathic abdominal pain, p < 0.001; abdominal pain after a meal, p < 0.001; abdominal pain during defecation, p = 0.008), while in the G1-FM group, some of the IBS symptoms significantly improved (mucus in stool, p = 0.031; bloating, p < 0.001). In group G3-K no significant improvement was seen. Based on the results of this open-label study, it was concluded that various dietary interventions in the treatment of IBS-M patients do not uniformly affect the course and outcomes of disease management. Rotation diets based on IgG show significantly better results compared to other diets.
Highlights
Irritable bowel syndrome (IBS) is a chronic gastrointestinal condition
It has been shown that a low FODMAP diet was effective in treating the functional symptoms of gastrointestinal conditions in comparison to a diet plan consistent with the recommendations of the UK National Institute for Health and Clinical Excellence (NICE) [9]
Study materials comprised of irritable bowel syndrome (IBS-M) patients diagnosed by an attending physician based on the Rome III criteria with no other digestive tract conditions that might influence the results of this study
Summary
Irritable bowel syndrome (IBS) is a chronic gastrointestinal condition. It is characterized by abdominal pains of different intensity, located usually on the left side of lower abdomen, combined with changes in stool consistency and/or bowel movements [1,2].Treating patients with IBS is a difficult and complex clinical problem; it appears that adequate dietary modifications can comprise an independent element of treatment.Some patients state that nutrition is an important factor influencing the clinical symptoms of IBS [3,4,5]. Irritable bowel syndrome (IBS) is a chronic gastrointestinal condition. It is characterized by abdominal pains of different intensity, located usually on the left side of lower abdomen, combined with changes in stool consistency and/or bowel movements [1,2]. Some patients state that nutrition is an important factor influencing the clinical symptoms of IBS [3,4,5]. This view is supported by reports indicating that 20% to 67% of patients with.
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