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https://doi.org/10.1016/j.bmcl.2009.09.067
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Cite Publication Date: Sep 22, 2009 | |
 Citations: 15 |
A CEM cell cDNA T7 phage display library was prepared and used to screen for activating enzymes of phosphoramidate prodrugs of AZT monophosphate. Although, inefficient compared to ribonucleotide based phosphoramidates, hHint 1 was identified as the likely intracellular pronucleotide activating enzyme.
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