Abstract
Objective: Acute respiratory tract infection (ARTI) is common and has the highest death rate in children, especially in growing countries such asIndonesia. The aim of the research is to identify drug-related problems (DRPs) in pediatric ARTI patients based on the DRP classification by Cipolle,Strand, and Morley, which included categories such as unnecessary drug therapy, need additional therapy, ineffective drug, dosage adjustments suchas too low or too high, and adverse drug reaction which is drug interaction.Methods: The design of the study was cross-sectional and descriptive with a retrospective method. The sample of the study was the overall prescriptionsto upper respiratory tract infection patients in Tebet Subdistrict Health Center from July to December 2018 that fulfilled all of the inclusion criteria,using the total sampling method. Total samples that were analyzed were from 179 sheets of prescription with a total of 498 prescriptions.Results: The results of the research based on each parameter were inaccurate drug selection (9.5%), inaccurate indication (12.8%), mismatched dose(79.9%), and drug interaction (0.6%).Conclusion: DRPs in ARTI pediatric patients resulted in a high-risk condition so that the health facilities need to improve their prescribing pattern andmonitor and manage each therapy as well as do a routine prescription assessment to minimize the incidence of DRPs and achieve a rational drug usage.
Highlights
Acute respiratory tract infection (ARTI) is one of many diseases caused by viruses or bacteria
The inclusion criteria of this study included prescriptions for pediatric ARTI patients with an ICD X code for upper ARTI, consisting of otitis media (H66), sinusitis (J01), pharyngitis (J02), tonsillitis (J03), and laryngitis-tracheitis (J04); prescriptions given to patients aged
ARTI cases most commonly happened in the age group of 3–6 years old (81.6%)
Summary
Acute respiratory tract infection (ARTI) is one of many diseases caused by viruses or bacteria. ARTI has a high mortality potential, especially in children [1]. This was shown by statistical data published by the World Health Organization in 2018 that stated that the world’s most frequent cause of mortality for children
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