Abstract

Histoplasma capsulatum is an environmental dimorphic fungus. H. capsulatum infections are primarily acquired, and there is no person-to-person transmission with the rare exception of organ transplantation. The objective of this research is to identify a B-cell and T-cell specific peptide vaccine for H. capsulatum by analyzing the outer membrane protein, predicting B-cell and T-cell epitopes, and selecting a candidate peptide vaccine with high homology to the pathogen and strong MHC I-binding potential

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