Abstract
A novel tartrate-derived guanidine accessed by a modular approach was identified to be an efficient catalyst for the Michael addition of 3-aminooxindoles to nitroolefins. A range of quaternary 3-aminooxindoles bearing adjacent quaternary–tertiary stereocenters were obtained in good to excellent yields (up to 95%) with good to excellent diastereo- and enantioselectivities (up to >20:1 dr and 98% ee).
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