Abstract
Cancer stem cells (CSCs) are a subpopulation of tumor cells associated with cancer initiation, progression and treatment failures of several malignancies, including oral squamous cells carcinoma (OSCC). Previous studies of our group isolated a high metastatic OSCC cell line (SCC9 ZsGreen LN1) by in vivo selection from the SCC9 cell line. Expression of surface markers for CSCs in SCC9 has not been described. Therefore, the goal of this study is to identify, characterize and compare the presence of CSCs in the SCC9 and SCC9 ZsGreen LN1 cell lines.
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