ID: 216887 Mechanisms of Increased Charge Injection Capacity of a Porous Injectable Electrode

Abstract

Applications of neuromodulation therapies are often limited by the invasiveness of the surgical procedure needed for implantation, high failure rates of implanted devices, and inconsistent therapeutic efficacy due to either off-target effects or lack of therapy at safe charge injection levels. To address several of these limitations we have developed the Injectrode, an injectable electrode designed to minimize surgical invasiveness and device failure while providing a high surface area for safe charge injection. In this work, we seek to understand the mechanisms and limitations of increased charge injection through a high surface area Injectrode formed with a microstructure of thin Pt-Ir wire wound into a flexible helical macroelectrode.