ID: 210553 Clinical Feasibility of ECAP-Controlled, Closed-Loop Spinal Cord Stimulation With Cervically Placed Leads

Abstract

Recent advances in spinal cord stimulation (SCS) have focused on two highly novel areas; Differential Target MultiplexedTM SCS (DTM) [1], which has demonstrated superior pain relief, and the spinal Evoked Compound Action Potential (ECAP), a bioelectrical signal used as a measure of neural activation with closed-loop (CL) SCS systems to compensate for motion at the electrode-tissue interface [2]. Due to thinner cerebral spinal fluid (CSF) and the large mobility in the cervical space compared to the thoracic space [3], the use of ECAP-controlled SCS systems for upper limb pain may reduce uncomfortable stimulation delivered to patients and decrease the variation in stimulation delivered to the cord. In this study, ECAP-controlled closed-loop DTMTM SCS was explored to assess feasibility with cervically placed SCS leads in an in-clinic environment.