Abstract
An adult dog were evaluated for treatment loss of consciousness, convulsions, and severe tremors after ingestion of xylitol, a sugar alcohol used as a sweetener in various products. Clinical findings were noted as loss of consciousness, convulsions, and severe tremors, while physio-pathological findings included moderately to severely elevated serum activities of liver enzymes, hypoglycaemia and hypophosphatemia. To correct hypoglycaemia, dextrose was administered intravenously and to provide electrolyte homeostasis Izolen P was administered intravenously. Also, Milk Thistle (Silymarin) & Beta Glucan Complex, Hepatiale Forte Advanced (S-adenosylmethionine), Evicap (Vit E) and Asist (acetylcysteine) were used to correct acute liver damage. Values measured after the applied treatments showed that blood glucose levels and liver enzymes returned to normal, and the patient was discharged. Xylitol causes hypoglycaemia and acute liver damage in dogs after ingestion. As a growing number of products contain xylitol, clinicians should be aware that ingestion of xylitol could have life-threatening effects. This case report also carries the distinction of being the first xylitol toxicity reported in dogs in Turkey.
Highlights
Xylitol toxicityIt has been suggested that the xylitol toxicity seen in dogs is related to severe hypoglycaemia caused by insulin secretion (Kuzuya et al, 1969)
An adult dog were evaluated for treatment loss of consciousness, convulsions, and severe tremors after ingestion of xylitol, a sugar alcohol used as a sweetener in various products
It has been suggested that the xylitol toxicity seen in dogs is related to severe hypoglycaemia caused by insulin secretion (Kuzuya et al, 1969)
Summary
It has been suggested that the xylitol toxicity seen in dogs is related to severe hypoglycaemia caused by insulin secretion (Kuzuya et al, 1969). It is reported that xylitol increases insulin secretion 2.5-7 times more than the same amount of glucose in dogs (Kuzuya et al, 1966). Typical clinical symptoms such as ataxia, seizures and vomiting are observed in xylitol intoxication in dogs. 0.15 g/kg xylitol has been reported to cause hypoglycaemia (Dunayer & Gwaltney-Brant, 2006). Researchers state that an increase in liver enzymes occurs 8-12 hours after ingestion of xylene in dogs and severe liver failure is formed (Murphy & Dunayer, 2018). The abdominal area was saggy and there were no abdominal pain symptoms
Sign-in/Register to view highlights & summary Sign-in/Register to access full text options 
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a call
