Hypoglycemic Effect of Olive Oil (Olea europea) on Alloxan- Induced Diabetic Albino Rats.

Abstract

This research work is aimed at investigating the hypoglycemic effect of olive oil obtained from the seeds of olive tree (Olea europea,) on alloxan-induced diabetic Albino rats. The results obtained show that olive oil (Olea europea) exhibit hypoglycemic effect on alloxan-induced diabetic Albino rats with the lower dose (150mg/kg/b.wt). as the most effective dose for the significant treatment of type 1 diabetes. Medium and High doses however showed an insignificant effect compared to the control groups. When the, standard drug (positive control) 60 mg/kg/b.wt was administered to the rats , the glucose level of the group 2 alloxan-induced diabetic rats decreased gradually to the range between the normal range 4.9-5.5 mg/dl according to the world health standard (W.H.O, 2014). During treatment, the body weight of the rats was observed to increase as the rats responded to the hypoglycemic effect of the oil treatment. As the treatment continues, the rats look healthier which shows a positive response to the olive oil treatment.