Abstract
Adrenocortical function was studied in 25 children with hypoglycemia, separated into two groups, depending on whether their height was above or below the third percentile. Plasma 17-hydroxycorticosteroid (17-OHCS) concentrations were not significantly different in the two groups, and were higher than normal in both. In both groups, the urinary 17-OHCS values were quite low considering the high plasma concentrations, but in neither group were they significantly lower than normal. Adrenal responsiveness to adrenocorticotropic hormone (ACTH) was normal as judged by the responses of both plasma and urinary 17-OHCS. In contrast, the control urinary 17-ketosteroid (17-KS) levels differed significantly from each other in the two groups, those in the group with severe growth retardation being significantly lower than normal and those in the other group being in the low normal range.
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