Abstract
Hypoglycaemia in the early neonatal period in newborns with risk factors
Highlights
Hypoglycaemia in a newborn is reduction of glucose concentration in blood below 2.6mmol/l in the neonatal period irrespective of the gestational age [1,2].Neonatal hypoglycaemia is a topical problem in neonatology and paediatric endocrinology
Problems of glycaemia monitoring during first days of life have been discussed as well as the strategy for management of newborns with the syndrome of hypoglycemia and evaluation of metabolism in brain neurons has been a matter of scientific research [3]
Hypoglycaemia persisting beyond the aforementioned period is based on transient hyperinsulinism, transient glucose deficiency medicine intake by the pregnant mother and/or the newborn as well as on a severe somatic pathology The above perinatal factors are predictors of transient impairments of carbohydrate metabolism in the early neonatal period
Summary
Hypoglycaemia in a newborn is reduction of glucose concentration in blood below 2.6mmol/l in the neonatal period irrespective of the gestational age [1,2].Neonatal hypoglycaemia is a topical problem in neonatology and paediatric endocrinology. Hypoglycaemia in a newborn is reduction of glucose concentration in blood below 2.6mmol/l in the neonatal period irrespective of the gestational age [1,2]. Hypoglycaemia persisting beyond the aforementioned period is based on transient hyperinsulinism (diabetes mellitus in the pregnant patient, perinatal asphyxia), transient glucose deficiency (intrauterine growth restriction, premature birth) medicine intake by the pregnant mother and/or the newborn (angiotensinconverting enzyme inhibitors, valproic acid, indomethacin, etc.) as well as on a severe somatic pathology (sepsis, CHD, etc.) The above perinatal factors are predictors of transient impairments of carbohydrate metabolism in the early neonatal period. The highest probability of blood glucose level decrease in risk group children exists for 42 hours after birth and may persist for 2-3 days [4,5]
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