Abstract
Hypervalent iodine reagents for heterocycle synthesis and functionalization Jiyun Sun,1 Daisy Zhang-Negrerie,2 Yunfei Du,1 Kang Zhao,1 1Tianjin Key Laboratory for Modern Drug Delivery and High-Efficiency, School of Pharmaceutical Science and Technology, Tianjin University, Tianjin, 2Concordia International School Shanghai, Shanghai, People’s Republic of China Abstract: Hypervalent iodine reagents have been vastly applied in many significant oxidative reactions. This surging interest in iodine reagents is mainly due to the very useful oxidizing properties, combined with their benign environmental character and commercial availability. In this review, we focus on the representative transformations that used the common hypervalent iodine reagents as oxidants in heterocycle synthesis and functionalizations, based on the type of the hypervalent iodine reagents. Keywords: hypervalent iodine reagent, heterocycle synthesis, heterocycle functionalization, oxidative reaction
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