Hypertrophic cardiomyopathy patients have a steep left ventricle to aortic root angle compared to normal as demonstrated on 3-D Tomographic Imaging: a case-control study

Deborah H Kwon,Harry Lever,Randolph M Setser,Milind Y Desai,Maran Thamilarasan,Scott D Flamm,Nicholas G Smedira,Zoran B Popovic,Paul Schoenhagen,Bruce W Lytle

doi:10.1186/1532-429x-11-s1-p143

Abstract

Hypertrophic cardiomyopathy (HCM) is characterized by disproportionate left ventricular (LV) hypertrophy, which cannot be attributed to other concomitant cardiac or systemic diseases. HCM can result in accelerated cardiac remodelling; thus affecting the pathophysiology of the disease. Because of an increased utilization of cardiac magnetic resonance (CMR) in the diagnosis and management of HCM, we have observed that a subgroup of HCM patients had a steep LV to aortic root angle (LVARA, Figure Figure11). Open in a separate window Figure 1 Quantification of LVARA using the 5 chamber view.

Highlights

Prophylactic implantation of a cardioverter/ defibrillator (ICD) has been shown to reduce mortality in patients with chronic myocardial infarction (CMI) and an increased risk for life threatening ventricular arrhythmia (VA)
The purpose of this study was to demonstrate a novel approach to imaging the vessel wall and vessel wall calcification using susceptibility weighted imaging [2] (SWI) with no need to suppress the signal from the blood
Optimizing the imaging parameters: The SWI sequence parameters were optimized to allow for the best visualization of the femoral artery lumen in the magnitude images and the arterial wall in the phase images

Summary

Introduction

Prophylactic implantation of a cardioverter/ defibrillator (ICD) has been shown to reduce mortality in patients with chronic myocardial infarction (CMI) and an increased risk for life threatening ventricular arrhythmia (VA). Methods: In 11 patients (age 0.7 – 27 years) with complex congenital heart disease, surgical questions were directed towards palliative or corrective surgery but consensus about the optimum treatment strategy was not reached using standard diagnostic tools including echocardiography, catheterization and conventional magnetic resonance imaging (MRI). In these patients, three-dimensional printed cast and virtual computer models of the heart were made on the basis of high-resolution whole-heart and/or cineMRI.

Objectives

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Discussion

Conclusion