Abstract

The risks of renal and cardiovascular disease — conditions that are often associated with long-standing hypertension — are far higher among people of African-American heritage than among those in other racial or ethnic groups. The African-American Study of Kidney Disease and Hypertension (AASK)1 is an important long-term study that compared standard with intensive therapy for hypertension among 1094 black patients with chronic kidney disease, defined as a glomerular filtration rate (GFR) of 20 to 65 ml per minute per 1.73 m2 of body-surface area. The study was conducted in a trial phase, followed by an observational cohort phase. The primary . . .

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