Abstract

The principal experimental methods in use for dynamic nuclear polarization (DNP) enhancement of sensitivity of nuclear magnetic resonance (NMR) spectra are summarized and compared. The sensitivity enhancements afforded by the use of DNP makes it possible to use NMR for studying aspects of molecular structure and function hitherto beyond the reach of conventional NMR methods. Applications of these methods in chemical and biochemical systems are introduced, together with applications in materials science and diagnostic medicine.

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