Hypereosinophilia in red scaly infants with scabies

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Scabies incognito is a rare disorder in the neonatal period with an unusual presentation of numerous mites.1Orkin M. Maibach H.I. Scabies and pediculosis.in: Freedberg I.M. Eisen A.Z. Wolff K. Dermatology in General Medicine. McGraw-Hill, New York1999: 2677-2680Google Scholar, 2Paller A.S. Scabies in infant and small children.Semin Dermatol. 1993; 12: 3PubMed Google Scholar Scabies may cause significant hypereosinophilia in the presence of mild reduction of immunity (eg, as from treatment with potent topical corticosteroid, abnormal leukocyte chemotaxis, and immature immune system in newborns). The presence of eosinophil peroxidase deficiency, a rare inherited anomaly, without evidence of disease3Walsh G.M. Eosinophil granule proteins and their role in disease.Curr Opin Hematol. 2001; 8: 28-33Crossref PubMed Scopus (91) Google Scholar is probably unrelated to scabies.Scabies should be considered in the differential diagnosis of presentation of “red scaly infant.” Complete blood count and microscopic examination of the skin should be performed. Infants with prolonged hypereosinophilia, regardless of etiology, may develop organ damage, especially cardiac.4Navajas A. Cardenal I. Pinan M.A. Ortiz A. Astigarraga I. Fdez-Teijeiro A. Hypereosinophilia due to myiasis.Acta Haematol. 1998; 99: 27-30Crossref PubMed Scopus (20) Google Scholar, 5Fauci A.S. Harley J.B. Roberts W.C. Ferrans V.J. Gralnick H.R. Bjornson B.H. The idiopathic hypereosinophilic syndrome: clinical pathophysiologic and therapeutic consideration.Ann Intern Med. 1982; 97: 78-92Crossref PubMed Google Scholar, 6Uttamchandani R.B. Trigo L.M. Poppiti Jr., R.J. Rozen S. Ratzan K.R. Eosinophilic pleural effusion in cutaneous myiasis.South Med J. 1989; 82: 1288-1291Crossref PubMed Scopus (19) Google Scholar Treatment for scabies might be considered even without clear evidence of S scabeii mites in the skin scraping. Scabies incognito is a rare disorder in the neonatal period with an unusual presentation of numerous mites.1Orkin M. Maibach H.I. Scabies and pediculosis.in: Freedberg I.M. Eisen A.Z. Wolff K. Dermatology in General Medicine. McGraw-Hill, New York1999: 2677-2680Google Scholar, 2Paller A.S. Scabies in infant and small children.Semin Dermatol. 1993; 12: 3PubMed Google Scholar Scabies may cause significant hypereosinophilia in the presence of mild reduction of immunity (eg, as from treatment with potent topical corticosteroid, abnormal leukocyte chemotaxis, and immature immune system in newborns). The presence of eosinophil peroxidase deficiency, a rare inherited anomaly, without evidence of disease3Walsh G.M. Eosinophil granule proteins and their role in disease.Curr Opin Hematol. 2001; 8: 28-33Crossref PubMed Scopus (91) Google Scholar is probably unrelated to scabies. Scabies should be considered in the differential diagnosis of presentation of “red scaly infant.” Complete blood count and microscopic examination of the skin should be performed. Infants with prolonged hypereosinophilia, regardless of etiology, may develop organ damage, especially cardiac.4Navajas A. Cardenal I. Pinan M.A. Ortiz A. Astigarraga I. Fdez-Teijeiro A. Hypereosinophilia due to myiasis.Acta Haematol. 1998; 99: 27-30Crossref PubMed Scopus (20) Google Scholar, 5Fauci A.S. Harley J.B. Roberts W.C. Ferrans V.J. Gralnick H.R. Bjornson B.H. The idiopathic hypereosinophilic syndrome: clinical pathophysiologic and therapeutic consideration.Ann Intern Med. 1982; 97: 78-92Crossref PubMed Google Scholar, 6Uttamchandani R.B. Trigo L.M. Poppiti Jr., R.J. Rozen S. Ratzan K.R. Eosinophilic pleural effusion in cutaneous myiasis.South Med J. 1989; 82: 1288-1291Crossref PubMed Scopus (19) Google Scholar Treatment for scabies might be considered even without clear evidence of S scabeii mites in the skin scraping.